Prof. dr. Hoeben is a graduate of Utrecht University (Biology) and performed his PhD research at Leiden University in the lab. of prof. Van der Eb. Here he developed gene-transfer vectors for gene therapy of hemophilia A. After various post-doctoral positions in Leiden, he was appointed as a professor at the Leiden University and Leiden University Medical Center in 2000, and heads the Virus and Stem Cell Biology lab. His main research interests are focused on the development of oncolytic viruses for cancer treatment and of gene transfer vectors for use in treatment of genetic disorders. Hoeben is a member of various professional associations and member of the Netherlands Commission on Genetic Modification COGEM.